Download e-book for kindle: Advances in the Treatment of Acute (Blastic) Leukemias by D. W. van Bekkum (auth.), Professor Georges Mathé (eds.)

By D. W. van Bekkum (auth.), Professor Georges Mathé (eds.)

ISBN-10: 3662349981

ISBN-13: 9783662349984

ISBN-10: 3662353342

ISBN-13: 9783662353349

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BrsEL, H. : Criteria for the evaluation of response to treatment in acute leukemia. Blood 11, 676-677 (1956). HrLL, J. , HrLL, R. : L-asparaginase therapy for leukemia and other malignant neoplasms. J. Amer. med. Ass. 202, 882-888 (1967). HASKELL, c. , CANELLOS, G. , LEVENTHAL, B. , CARBONE, P. , SERPICK, A. , HANSEN, H. : Letter to the editor: L-asparaginase toxicity. Cancer Res. 29, 974-975 (1969). CANELLOS, G. , HASKELL, C. , CARBONE, P. : Hypoalbuminemic and hypocholesterolemic effect of L-asparaginase (NSC-109229) treatment in man: preliminary report.

1) L-asparaginase can induce complete remissions in acute lymphoblastic leukaemias at a very late stage of the disease, and resistant to most other chemotherapies. In our experience these remissions were obtained in 12 treatments out of 31, or about 40 p. 100. 2) L-asparaginase has a certain leukopenia producing effect, but hardly aggravates the pre-existing leukopenia by its use. It can therefore be used during complementary chemotherapy of acute leukaemias in non-visible phases during these periods of hypoplasia.

ETTGEN, H. , ScHULTEN, H. : Hemmung maligner Neoplasien des Menschen durch L-Asparaginase. Klin. Wschr. 47, 65 (1969). 12. ÜETTGEN, H. : Paper presented at the meeting of the Paul-Ehrlich-Gesellschaft Wuppertal- Asparaginase-Therapie der Leukämien. May 1969. 13. ScHMIDT, C. : Zur Enzymtherapie der Leukämien. Dtsch. med. r. 93, 2299 (1968). 14. STIER, H. , ScHMIDT, C. , GALLMEIER, W. : Das Blutgerinnungssystem während der Leukämiebehandlung mit L-Asparaginase in Chemo- und Immuntherapie der Leukosen und malignen Lymphome.

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Advances in the Treatment of Acute (Blastic) Leukemias by D. W. van Bekkum (auth.), Professor Georges Mathé (eds.)


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