Advances in Cancer Research, Vol. 107 by George F. Vande Woude PDF

By George F. Vande Woude

ISBN-10: 0123747708

ISBN-13: 9780123747709

Advances in melanoma study presents useful info at the fascinating and fast-moving box of melanoma learn. right here, once more, notable and unique experiences are offered on numerous subject matters

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177, 5014–5023. 30 Amir Sharabi and Nechama Haran Ghera Brimnes, M. , Svane, I. , and Johnsen, H. E. (2006). Impaired functionality and phenotypic profile of dendritic cells from patients with multiple myeloma. Clin. Exp. Immunol. 144, 76–84. , and Cooke, A. (2008). Immune-potentiating effects of the chemotherapeutic drug cyclophosphamide. Crit. Rev. Immunol. 28, 109–126. , Butterfield, C. , Kraling, B. , O’Reilly, M. , and Folkman, J. (2000). Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.

2003). At different intervals after the initial high-dose CYC treatment (80, 60, or 45 days), low-dose CYC (100 mg/kg) was administered repeatedly at 45-day intervals (protocol schedules are presented in Fig. 3A). In group C (n¼10), 30% (3/10) developed MM at 200Æ27 days. In group D (n¼10), 20% (2/10) developed MM at 191Æ4 days and in group E (n¼10), 10% (1/10) developed MM at 220 days. Chemoimmunotherapy of Mouse Multiple Myeloma 25 C. Residual Tumor Cells Initial antitumor treatment may reduce the tumor mass to minimal residual disease, thereby altering the balance of the disease.

Smyth, M. , and Godfrey, D. I. (2000). NKT cells and tumor immunity—A double-edged sword. Nat. Immunol. 1, 459–460. Smyth, M. , Crowe, N. , and Godfrey, D. I. (2002). NKT cells—Conductors of tumor immunity? Curr. Opin. Immunol. 14, 165–171. Sutmuller, R. , van Duivenvoorde, L. , Schumacher, T. , Wildenberg, M. , Allison, J. , Toes, R. , and Melief, C. J. (2001). Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(þ) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses.

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Advances in Cancer Research, Vol. 107 by George F. Vande Woude

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